| Round 1 | Round 2 | Round 3 |
|---|---|---|
Tabla general – Apertura 2022
| Pos | Club | Pts | P | G | E | D | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Club América | 38 | 17 | 12 | 2 | 3 | 38 | 17 | 21 |
| 2 |  Monterrey | 35 | 17 | 10 | 5 | 2 | 29 | 13 | 16 |
| 3 |  Santos | 33 | 17 | 10 | 3 | 4 | 38 | 21 | 17 |
| 4 |  Pachuca | 32 | 17 | 9 | 5 | 3 | 28 | 15 | 13 |
| 5 |  Tigres | 30 | 17 | 9 | 3 | 5 | 24 | 14 | 10 |
| 6 |  Toluca | 27 | 17 | 7 | 6 | 4 | 27 | 23 | 4 |
| 7 |  Cruz Azul | 24 | 17 | 7 | 3 | 7 | 26 | 34 | -8 |
| 8 |  Chivas | 22 | 17 | 5 | 7 | 5 | 19 | 17 | 2 |
| 9 |  Puebla | 22 | 17 | 4 | 10 | 3 | 25 | 23 | 2 |
| 10 |  León | 22 | 17 | 6 | 4 | 7 | 25 | 29 | -4 |
| 11 |  Juárez | 19 | 17 | 4 | 7 | 6 | 17 | 18 | -1 |
| 12 |  Necaxa | 19 | 17 | 5 | 4 | 8 | 19 | 26 | -7 |
| 13 |  San Luis | 18 | 17 | 4 | 6 | 7 | 15 | 23 | -8 |
| 14 |  Mazatlan FC | 17 | 17 | 3 | 8 | 6 | 17 | 24 | -7 |
| 15 |  Xolos | 17 | 17 | 4 | 5 | 8 | 18 | 30 | -12 |
| 16 |  Pumas | 14 | 17 | 2 | 8 | 7 | 21 | 31 | -10 |
| 17 |  Atlas | 13 | 17 | 3 | 4 | 10 | 16 | 27 | -11 |
| 18 |  Querétaro | 9 | 17 | 1 | 6 | 10 | 18 | 35 | -17 |